Combinatorial code governing cellular responses to complex stimuli
نویسندگان
چکیده
منابع مشابه
Combinatorial code governing cellular responses to complex stimuli
Cells adapt to their environment through the integration of complex signals. Multiple signals can induce synergistic or antagonistic interactions, currently considered as homogenous behaviours. Here, we use a systematic theoretical approach to enumerate the possible interaction profiles for outputs measured in the conditions 0 (control), signals X, Y, X+Y. Combinatorial analysis reveals 82 poss...
متن کاملThe responses of horses to predator stimuli
It is not known whether the instincts of wild horses have remained strong during their centuries of domestication. Knowledge of this matter would give riders the opportunity to know more about the behavior of horses and consequently about safety for both horses and riders. In this current research, we studied the behavior of fifteen Caspian miniature horses of different ages and sexes using sti...
متن کاملA contrast and surface code explains complex responses to black and white stimuli in V1.
We investigated the cortical mechanisms underlying the visual perception of luminance-defined surfaces and the preference for black over white stimuli in the macaque primary visual cortex, V1. We measured V1 population responses with voltage-sensitive dye imaging in fixating monkeys that were presented with white or black squares of equal contrast around a mid-gray. Regions corresponding to the...
متن کاملCellular and molecular responses of cultured neurons to stressful stimuli.
Synaptic function is critical for the brain to process experiences dictated by the environment requiring change over the lifetime of the organism. Experience-driven adaptation requires that receptors, signal transduction pathways, transcription and translational mechanisms within neurons respond rapidly over its lifetime. Adaptive responses communicated through the rapid firing of neurons are d...
متن کاملProbing cellular mechanical responses to stimuli using ballistic intracellular nanorheology.
We describe a new method to measure the local and global micromechanical properties of the cytoplasm of single living cells in their physiological milieu and subjected to external stimuli. By tracking spontaneous, Brownian movements of individual nanoparticles of diameter>or=100 nm distributed within the cell with high spatial and temporal resolutions, the local viscoelastic properties of the i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Communications
سال: 2015
ISSN: 2041-1723
DOI: 10.1038/ncomms7847